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In vivo and in vitro evidence for in situ activation and selective covalent binding of acetaminophen (APAP) in mouse kidney.
- Source :
-
Advances in experimental medicine and biology [Adv Exp Med Biol] 1991; Vol. 283, pp. 711-6. - Publication Year :
- 1991
- Subjects :
- Acetaminophen pharmacokinetics
Acetaminophen toxicity
Animals
Biotransformation
Cytochrome P-450 Enzyme System metabolism
Immunohistochemistry
In Vitro Techniques
Kidney Tubules, Proximal cytology
Kidney Tubules, Proximal drug effects
Male
Mice
Mice, Inbred ICR
Acetaminophen metabolism
Kidney Tubules, Proximal metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0065-2598
- Volume :
- 283
- Database :
- MEDLINE
- Journal :
- Advances in experimental medicine and biology
- Publication Type :
- Academic Journal
- Accession number :
- 2069045
- Full Text :
- https://doi.org/10.1007/978-1-4684-5877-0_92