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Effects of a very-low-calorie diet on long-term glycemic control in obese type 2 diabetic subjects.
- Source :
-
Archives of internal medicine [Arch Intern Med] 1991 Jul; Vol. 151 (7), pp. 1334-40. - Publication Year :
- 1991
-
Abstract
- We tested the hypothesis that the use of a very-low-calorie diet (VLCD) in combination with behavior modification would promote long-term glycemic control in obese type 2 diabetic subjects. Thirty-six diabetic subjects were randomly assigned to a standard behavior therapy program or to a behavior therapy program that included an 8-week period of VLCD. The behavior therapy group consumed a balanced diet of 4200 to 6300 J/d throughout the 20-week program. The VLCD group consumed a balanced diet of 4200 to 6300 J for weeks 1 to 4, followed by a VLCD (1680 J/d of lean meat, fish, and fowl) for weeks 5 to 12. The VLCD group then gradually reintroduced other foods during weeks 13 to 16 and consumed a balanced diet of 4200 to 6300 J/d for weeks 17 to 20. Thirty-three of the 36 subjects completed the 20-week program and the 1-year follow-up. Use of the VLCD produced greater decreases in fasting glucose at the end of the 20-week program and at 1-year follow-up and greater long-term reductions in HbA1. The VLCD group also had greater weight losses at week 20, but weight losses from pretreatment to 1-year follow-up were similar in the two treatment groups. The improved glycemic control with the VLCD appeared to be due to increased insulin secretion, but further research is needed to confirm this.
- Subjects :
- Adult
Aged
Diabetes Mellitus, Type 2 complications
Diabetes Mellitus, Type 2 metabolism
Electrocardiography
Energy Intake
Exercise
Female
Follow-Up Studies
Hemoglobin A analysis
Humans
Insulin blood
Lipids blood
Male
Middle Aged
Monitoring, Physiologic
Obesity complications
Patient Compliance
Weight Loss physiology
Blood Glucose metabolism
Diabetes Mellitus, Type 2 diet therapy
Diet, Reducing
Obesity diet therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0003-9926
- Volume :
- 151
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Archives of internal medicine
- Publication Type :
- Academic Journal
- Accession number :
- 2064484