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Antibacterial activity of a triclosan-containing resin composite matrix against three common oral bacteria.
- Source :
-
Journal of materials science. Materials in medicine [J Mater Sci Mater Med] 2010 Nov; Vol. 21 (11), pp. 2971-7. Date of Electronic Publication: 2010 Jul 17. - Publication Year :
- 2010
-
Abstract
- This study investigated the antibacterial effect of a resin composite matrix with or without incorporated triclosan (0.3 wt%) on Streptococcus mutans, Actinomyces viscosus and Lactobacillus casei. In the quantitative assay, bacterial suspensions were filled into 20-μl cavities within temporary restorative resins. After 0, 4, 8, 12, 24 and 48 h of incubation, the suspensions were removed from the restoratives and the numbers of viable bacteria were determined. Bacterial suspensions incubated without restoratives served as the controls. Ten replicates were carried out for each experiment. The resin composite containing triclosan demonstrated variable degrees of antibacterial activity against the microorganisms, revealing a significant inhibitory effect on S. mutans within 12 h compared to the control. The viable counts of A. viscosus significantly decreased after 24 h. A significant reduction of L. casei was observed after 48 h. The unloaded resin composite did not reveal a marked antibacterial effect. The resin composite loaded with triclosan might be beneficial in preventing cavity contamination and minimizing the risk of pulpal irritation in the short-term.
- Subjects :
- Actinomyces viscosus drug effects
Actinomyces viscosus growth & development
Anti-Bacterial Agents administration & dosage
Anti-Bacterial Agents chemical synthesis
Anti-Bacterial Agents chemistry
Colony Count, Microbial
Composite Resins chemistry
Composite Resins pharmacology
Drug Carriers chemistry
Drug Carriers pharmacology
Humans
Lacticaseibacillus casei drug effects
Lacticaseibacillus casei growth & development
Materials Testing
Microbial Sensitivity Tests
Microbial Viability drug effects
Models, Biological
Resins, Synthetic chemical synthesis
Resins, Synthetic chemistry
Resins, Synthetic pharmacology
Streptococcus mutans drug effects
Streptococcus mutans growth & development
Anti-Bacterial Agents pharmacology
Composite Resins chemical synthesis
Drug Carriers chemical synthesis
Mouth microbiology
Triclosan administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1573-4838
- Volume :
- 21
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Journal of materials science. Materials in medicine
- Publication Type :
- Academic Journal
- Accession number :
- 20640491
- Full Text :
- https://doi.org/10.1007/s10856-010-4126-1