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Refining the definition of hypereosinophilic syndrome.
- Source :
-
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2010 Jul; Vol. 126 (1), pp. 45-9. - Publication Year :
- 2010
-
Abstract
- Because of advances in our understanding of the hypereosinophilic syndrome (HES) and the availability of novel therapeutic agents, the original criteria defining these disorders are becoming increasingly problematic. Here, we discuss shortcomings with the current definition of HES and recent developments in the classification of these disorders. Despite significant progress in our understanding of the pathogenesis of some forms of HES, the current state of knowledge is still insufficient to formulate a new comprehensive etiologic definition of HESs. Nevertheless, we suggest a new working definition that overcomes some of the most obvious limitations with the original definition.
Details
- Language :
- English
- ISSN :
- 1097-6825
- Volume :
- 126
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Journal of allergy and clinical immunology
- Publication Type :
- Academic Journal
- Accession number :
- 20639008
- Full Text :
- https://doi.org/10.1016/j.jaci.2010.03.042