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Electrophysiological and morphological development of the inner ear in Belgian Waterslager canaries.
- Source :
-
Hearing research [Hear Res] 2010 Oct 01; Vol. 269 (1-2), pp. 56-69. Date of Electronic Publication: 2010 Jul 16. - Publication Year :
- 2010
-
Abstract
- Belgian Waterslager (BW) canaries have an inherited hearing loss due to missing and abnormal hair cells, but it is unclear whether the loss is congenital or developmental. We used auditory brainstem responses and scanning electron microscopy to describe the development of auditory sensitivity and hair cell abnormalities in BW and non-BW canaries. In both strains, adult ABR thresholds were higher than behavioral thresholds, but BW canaries exhibited higher thresholds than non-BW canaries across all frequencies. Immediately post-hatch, ABR thresholds and hair cell numbers were similar in both strains. Two weeks later, thresholds were significantly higher in BW canaries, and hair cell number progressively decreased as the birds aged. These data show that in BW canaries: the peripheral auditory system is functionally similar to non-BW canary from hatch to 2 weeks, ABR thresholds improve during this developmental period, actually becoming better than those of adults, but then worsen as the bird continues to age. Hair cell number and appearance is similar to non-BW canaries at hatch but progressively declines after 30 days of age. These data show that the hearing loss characteristic of BW canaries is, at least in part, developmental and is established by the time song learning begins.
- Subjects :
- Acoustic Stimulation
Aging pathology
Animals
Auditory Threshold physiology
Evoked Potentials, Auditory, Brain Stem physiology
Hair Cells, Auditory, Inner pathology
Hair Cells, Auditory, Inner physiology
Hair Cells, Auditory, Inner ultrastructure
Microscopy, Electron, Scanning
Models, Animal
Reaction Time physiology
Aging physiology
Canaries growth & development
Canaries physiology
Ear, Inner growth & development
Ear, Inner physiopathology
Electrophysiological Phenomena physiology
Hearing Loss physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-5891
- Volume :
- 269
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Hearing research
- Publication Type :
- Academic Journal
- Accession number :
- 20638464
- Full Text :
- https://doi.org/10.1016/j.heares.2010.07.003