Measles outbreak in Tanzania, 2006-2007.

Authors :: Goodson JL
Perry RT
Mach O
Manyanga D
Luman ET
Kitambi M
Kibona M
Wiesen E
Cairns KL
Source :: Vaccine [Vaccine] 2010 Aug 23; Vol. 28 (37), pp. 5979-85. Date of Electronic Publication: 2010 Jul 15.
Publication Year :: 2010
Abstract: We conducted a measles outbreak investigation in Dar es Salaam, Tanzania. Surveillance data were analyzed; a susceptibility profile developed, and case-control study conducted. The age distribution of cases peaked among those <2, 5-7, and > or =18 years, corresponding to the age distribution of susceptibles. Risk factors included being unvaccinated (aOR=5.7, p<0.01) or having received one dose of vaccine compared to two (aOR=2.4, p=0.01), being younger, and having a less-educated caretaker. Vaccine effectiveness was 88% (one dose) and 96% (two doses). Results highlight the importance of receiving one dose of measles vaccine, and the added benefit of two doses.<br /> (Published by Elsevier Ltd.)