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[Treatments for cardiovascular risk factors and screening for coronary artery disease in type 2 diabetes mellitus].
- Source :
-
Revue medicale suisse [Rev Med Suisse] 2010 Jun 09; Vol. 6 (252), pp. 1176-8, 1180-1. - Publication Year :
- 2010
-
Abstract
- The recent ACCORD and DIAD studies revealed results which could modify treatments and the screening of diabetes vascular complications. Indeed, ACCORD shows no benefit on the prevention of diabetes vascular complications by aggressive treatment of hypertension or the combined treatment of the dyslipidemia. The intensive treatment of the blood glucose, if associated with severe hypoglycemias, increases mortality. DIAD revealed 20% of silent myocardial ischaemia in diabetic patients but no beneficial effect on the cardiovascular mortality. A careful reading of these studies in the light of long term studies such as UKPDS and STENO reveals that these negative results are generated by a too short follow-up and too aggressive objectives. The long term studies reveal that more realistic objectives remain beneficial.
- Subjects :
- Coronary Disease epidemiology
Coronary Disease prevention & control
Dyslipidemias complications
Dyslipidemias drug therapy
Evidence-Based Medicine
Fenofibrate therapeutic use
Humans
Hypertension complications
Hypertension drug therapy
Hypolipidemic Agents therapeutic use
Mass Screening
Randomized Controlled Trials as Topic
Risk Factors
Coronary Disease diagnosis
Coronary Disease etiology
Diabetes Mellitus, Type 2 complications
Subjects
Details
- Language :
- French
- ISSN :
- 1660-9379
- Volume :
- 6
- Issue :
- 252
- Database :
- MEDLINE
- Journal :
- Revue medicale suisse
- Publication Type :
- Academic Journal
- Accession number :
- 20614751