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[Treatments for cardiovascular risk factors and screening for coronary artery disease in type 2 diabetes mellitus].

Authors :
Ruiz J
Egli M
Gianinazzi F
Izzo F
Voeffray Favre AC
Rossi I
Bodenman P
Source :
Revue medicale suisse [Rev Med Suisse] 2010 Jun 09; Vol. 6 (252), pp. 1176-8, 1180-1.
Publication Year :
2010

Abstract

The recent ACCORD and DIAD studies revealed results which could modify treatments and the screening of diabetes vascular complications. Indeed, ACCORD shows no benefit on the prevention of diabetes vascular complications by aggressive treatment of hypertension or the combined treatment of the dyslipidemia. The intensive treatment of the blood glucose, if associated with severe hypoglycemias, increases mortality. DIAD revealed 20% of silent myocardial ischaemia in diabetic patients but no beneficial effect on the cardiovascular mortality. A careful reading of these studies in the light of long term studies such as UKPDS and STENO reveals that these negative results are generated by a too short follow-up and too aggressive objectives. The long term studies reveal that more realistic objectives remain beneficial.

Details

Language :
French
ISSN :
1660-9379
Volume :
6
Issue :
252
Database :
MEDLINE
Journal :
Revue medicale suisse
Publication Type :
Academic Journal
Accession number :
20614751