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Postexposure treatment of Marburg virus infection.

Authors :
Geisbert TW
Hensley LE
Geisbert JB
Leung A
Johnson JC
Grolla A
Feldmann H
Source :
Emerging infectious diseases [Emerg Infect Dis] 2010 Jul; Vol. 16 (7), pp. 1119-22.
Publication Year :
2010

Abstract

Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.

Details

Language :
English
ISSN :
1080-6059
Volume :
16
Issue :
7
Database :
MEDLINE
Journal :
Emerging infectious diseases
Publication Type :
Academic Journal
Accession number :
20587184
Full Text :
https://doi.org/10.3201/eid1607.100159