Back to Search
Start Over
[Diseases of the outer eye in rheumatoid arthritis].
- Source :
-
Zeitschrift fur Rheumatologie [Z Rheumatol] 2010 Jul; Vol. 69 (5), pp. 403-10. - Publication Year :
- 2010
-
Abstract
- Eye involvement is a frequent finding in patients with rheumatoid arthritis and may represent the leading clinical manifestation of disease. In this context, all components of the visual organ might be affected. The main spectrum of eye involvement comprises keratoconjunctivitis sicca, episcleritis and scleritis as well as ulcerative keratitis. As with the underlying disease, autoimmune reactions based on a patient's genetic predisposition are assumed to be of significance in disease pathogenesis. Emerging evidence also points to additional morphological and physiological ocular characteristics in the pathogenesis of the various ocular pathologies. This article gives an overview of clinical aspects, pathogenetic background as well as therapeutic options for ocular involvement in rheumatoid arthritis.
- Subjects :
- Administration, Oral
Adolescent
Adrenal Cortex Hormones administration & dosage
Adrenal Cortex Hormones adverse effects
Adult
Aged
Antirheumatic Agents administration & dosage
Antirheumatic Agents adverse effects
Arthritis, Rheumatoid immunology
Arthritis, Rheumatoid pathology
Arthritis, Rheumatoid therapy
Autoantibodies blood
Child
Contraindications
Corneal Ulcer diagnosis
Corneal Ulcer immunology
Corneal Ulcer pathology
Corneal Ulcer therapy
Cytokines blood
Diagnosis, Differential
Eye Diseases immunology
Eye Diseases pathology
Eye Diseases therapy
Female
Fluorescein Angiography
Humans
Immunosuppressive Agents administration & dosage
Immunosuppressive Agents adverse effects
Keratoconjunctivitis Sicca diagnosis
Keratoconjunctivitis Sicca immunology
Keratoconjunctivitis Sicca pathology
Keratoconjunctivitis Sicca therapy
Keratoplasty, Penetrating
Male
Middle Aged
Ophthalmic Solutions
Rheumatic Diseases diagnosis
Rheumatic Diseases immunology
Rheumatic Diseases pathology
Rheumatic Diseases therapy
Scleritis diagnosis
Scleritis immunology
Scleritis pathology
Scleritis therapy
Young Adult
Anterior Eye Segment immunology
Anterior Eye Segment pathology
Arthritis, Rheumatoid diagnosis
Eye Diseases diagnosis
Subjects
Details
- Language :
- German
- ISSN :
- 1435-1250
- Volume :
- 69
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Zeitschrift fur Rheumatologie
- Publication Type :
- Academic Journal
- Accession number :
- 20559644
- Full Text :
- https://doi.org/10.1007/s00393-009-0577-5