Back to Search
Start Over
Escitalopram for persistent symptoms of generalized anxiety disorder after CBT: a pilot study.
- Source :
-
The Journal of nervous and mental disease [J Nerv Ment Dis] 2010 Jun; Vol. 198 (6), pp. 458-61. - Publication Year :
- 2010
-
Abstract
- Cognitive behavioral therapy (CBT) and pharmacotherapy are each efficacious for generalized anxiety disorder (GAD). It is not known, however, whether GAD partial and nonresponders to one treatment modality benefit from the other. This study explored acceptability and efficacy of escitalopram for persons with persistent GAD symptoms after a course of CBT. Twenty-four patients with GAD were treated with CBT and 15 completed at least 12 sessions. Eight completers continued to have clinically significant symptoms and were offered 12 weeks of treatment with escitalopram, and 7 started escitalopram treatment. During CBT, patients evidenced significant improvement in GAD, depression, and quality of life. During escitalopram treatment, patients evidenced trends toward further improvement in GAD, depression, and quality of life. Escitalopram phase completers had initially reported low-to-moderate preferences for medication treatment. Escitalopram may benefit GAD patients with clinically significant symptoms after CBT and merits further study under controlled conditions in a larger sample.
- Subjects :
- Adolescent
Adult
Aged
Anxiety Disorders diagnosis
Citalopram adverse effects
Combined Modality Therapy
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
Male
Middle Aged
Patient Satisfaction
Pilot Projects
Psychiatric Status Rating Scales
Quality of Life
Selective Serotonin Reuptake Inhibitors adverse effects
Severity of Illness Index
Surveys and Questionnaires
Treatment Outcome
Anxiety Disorders drug therapy
Anxiety Disorders therapy
Citalopram therapeutic use
Cognitive Behavioral Therapy methods
Selective Serotonin Reuptake Inhibitors therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1539-736X
- Volume :
- 198
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The Journal of nervous and mental disease
- Publication Type :
- Academic Journal
- Accession number :
- 20531128
- Full Text :
- https://doi.org/10.1097/NMD.0b013e3181da4d77