Are Cox-2 drugs the second line option in indomethacin responsive headaches?

Authors :: Porta-Etessam J
Cuadrado M
Rodríguez-Gómez O
García-Ptacek S
Valencia C
Source :: The journal of headache and pain [J Headache Pain] 2010 Oct; Vol. 11 (5), pp. 405-7. Date of Electronic Publication: 2010 Jun 02.
Publication Year :: 2010
Abstract: Paroxysmal hemicrania and hemicrania continua are both indomethacin-responsive headaches. Although indomethacin use to be well tolerated, some patients developed gastrointestinal side effects. We report four cases of hemicrania continua and a patient suffering chronic paroxysmal hemicrania completely responsive to celecoxib. In our experience celecoxib is a good option treatment for patients suffering from hemicrania continua or chronic paroxysmal hemicranea that presents indomethacin adverse effects.