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Anticoccidial activity of maslinic acid against infection with Eimeria tenella in chickens.
- Source :
-
Parasitology research [Parasitol Res] 2010 Aug; Vol. 107 (3), pp. 601-4. Date of Electronic Publication: 2010 May 25. - Publication Year :
- 2010
-
Abstract
- We propose maslinic acid (2-alpha, 3-beta-dihydroxiolean-12-en-28-oic acid), found in the leaves and fruit of the olive tree (Olea europaea L.), as a new natural coccidiostatic product against Eimeria tenella. Its action in infected animals has been compared with animals treated with sodium salinomycin. The lesion index (LS), the oocyst index (OI) and the anticoccidial index (ACI) were studied with regard to the weight of the chicks. The ACI for maslinic acid was 210.27 and for sodium salinomycin 173.09. Similarly, both LS and OI decreased in the groups treated with maslinic acid. A considerable increase in weight was found in the chicks treated with maslinic acid compared with those in the control group. Histopathological studies of the caecum at 120 h post-infection showed that the infection rate decreased significantly in chicks treated with maslinic acid.
- Subjects :
- Animals
Cecum parasitology
Cecum pathology
Chickens
Coccidiosis drug therapy
Coccidiosis pathology
Coccidiostats administration & dosage
Olea chemistry
Poultry Diseases parasitology
Poultry Diseases pathology
Pyrans administration & dosage
Pyrans therapeutic use
Treatment Outcome
Triterpenes administration & dosage
Coccidiosis veterinary
Coccidiostats therapeutic use
Eimeria tenella drug effects
Poultry Diseases drug therapy
Triterpenes therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1432-1955
- Volume :
- 107
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Parasitology research
- Publication Type :
- Academic Journal
- Accession number :
- 20499099
- Full Text :
- https://doi.org/10.1007/s00436-010-1901-3