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Vitamin D and bone health among children with epilepsy.
- Source :
-
Pediatric neurology [Pediatr Neurol] 2010 Jun; Vol. 42 (6), pp. 385-93. - Publication Year :
- 2010
-
Abstract
- The lay media and scientific literature have focused increasing attention on vitamin D deficiency and insufficiency in recent years. Low vitamin D levels confer increased an risk of abnormal bone mineralization, and are linked to poor bone health in epilepsy patients. However, vitamin D is not the only determinant of bone health in children with epilepsy. Anticonvulsant medications, in addition to features and comorbidities of epilepsy and coexisting neurologic diseases, are important factors in this complex topic. We review the basic metabolism of vitamin D in terms of bone health among children with epilepsy. We also discuss the literature regarding vitamin D and bone mineral density in this population. Finally, we suggest algorithms for screening and treating vitamin D insufficiency in these patients.<br /> (Copyright 2010 Elsevier Inc. All rights reserved.)
- Subjects :
- Anticonvulsants therapeutic use
Bone Density drug effects
Bone Density physiology
Bone and Bones drug effects
Child
Epilepsy complications
Epilepsy drug therapy
Humans
Vitamin D Deficiency complications
Vitamin D Deficiency drug therapy
Bone and Bones physiopathology
Epilepsy physiopathology
Vitamin D therapeutic use
Vitamin D Deficiency physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-5150
- Volume :
- 42
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Pediatric neurology
- Publication Type :
- Academic Journal
- Accession number :
- 20472188
- Full Text :
- https://doi.org/10.1016/j.pediatrneurol.2009.12.005