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Fatal peritonitis caused by Rhizopus microsporus.
- Source :
-
Medical mycology [Med Mycol] 2010 Dec; Vol. 48 (8), pp. 1096-8. Date of Electronic Publication: 2010 May 14. - Publication Year :
- 2010
-
Abstract
- A 52-year-old woman with a history of Crohn's disease was admitted due to peritonitis which followed an intestinal perforation. After transitory treatment with voriconazole, resolution of the infection was complicated by recurring peritonitis resulting from necrosis and perforation of the left colon which ultimately lead to the death of the patient. Microscopic examination of the peritoneal fluid revealed the presence of broad, irregular hyphae and culture of the fluid yielded Rhizopus microsporus. The identification of the fungus was confirmed by its characteristic microscopic morphology and sequencing of the ITS region of the rDNA. The histopathologic examination of the colon tissue demonstrated the presence of broad, non-septate hyphae and the same fungus was again isolated in culture.
- Subjects :
- Antifungal Agents therapeutic use
Colon pathology
Crohn Disease complications
Fatal Outcome
Female
Humans
Middle Aged
Mucormycosis microbiology
Mucormycosis pathology
Peritonitis pathology
Pyrimidines therapeutic use
Triazoles therapeutic use
Voriconazole
Intestinal Perforation complications
Mucormycosis diagnosis
Peritonitis microbiology
Rhizopus isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1460-2709
- Volume :
- 48
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Medical mycology
- Publication Type :
- Academic Journal
- Accession number :
- 20465520
- Full Text :
- https://doi.org/10.3109/13693786.2010.485281