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Time to stable ST-segment recovery following primary angioplasty is predictive of regional wall motion score and clinical outcome.

Authors :
Albertal M
Cura F
Thierer J
Trivi M
Escudero AG
Padilla LT
Belardi JA
Source :
Angiology [Angiology] 2010 Oct; Vol. 61 (7), pp. 638-42. Date of Electronic Publication: 2010 May 12.
Publication Year :
2010

Abstract

We report the time to stable ST-segment reperfusion (TSTR) after primary angioplasty and its relationship with the clinical results; 137 patients who underwent primary angioplasty were included as part of the analysis. All patients had 24 hours ST-segment monitoring. Time to stable STR was defined as the beginning of ST-segment reperfusion (STR) lasting >4 hours without ST-segment reelevation. Six-month mortality was associated with slower TSTR (median 166.5 vs 6 minute, P = .001). Time to stable STR cutoff value of 136.5 minutes was identified as the best mortality predictor (area under the curve: 0.86, P = .001). Multivariate analysis identified Killip class > or = 2 (P = .042), TSTR cutoff value (P = .002), and final thrombolysis myocardial infarction (TIMI) flow grade III (P = .067) as predictors of 6-month mortality. Time to stable STR may be a novel continuous electrocardiogram (ECG) parameter following primary angioplasty, which can identify high-risk patients that need to be considered for additional treatments.

Details

Language :
English
ISSN :
1940-1574
Volume :
61
Issue :
7
Database :
MEDLINE
Journal :
Angiology
Publication Type :
Academic Journal
Accession number :
20462897
Full Text :
https://doi.org/10.1177/0003319710369099