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Acute disseminating encephalomyelitis following legionnaires disease.
- Source :
-
Archives of neurology [Arch Neurol] 2010 May; Vol. 67 (5), pp. 623-6. - Publication Year :
- 2010
-
Abstract
- Objective: To describe 2 patients presenting with severe neurological deficits and extensive lesions on brain magnetic resonance imaging after having experienced Legionella pneumonia.<br />Design: Case reports.<br />Setting: University hospital.<br />Patients: Two patients who developed severe neurological symptoms, including encephalopathic signs, following Legionella infection, with widespread lesions on magnetic resonance imaging compatible with demyelination.<br />Results: After extensive ancillary investigations, a diagnosis of acute disseminating encephalomyelitis was considered most likely. Steroid therapy was initiated in 1 of the patients, followed by plasmapheresis. In both patients, clinical and radiological signs gradually recovered, with only slight residual deficits.<br />Conclusion: In patients presenting with neurological symptoms after an episode of pneumonia, Legionella infection and a subsequent immune-mediated process such as acute disseminating encephalomyelitis should be considered.
- Subjects :
- Autoantibodies blood
Brain immunology
Demyelinating Autoimmune Diseases, CNS microbiology
Demyelinating Autoimmune Diseases, CNS pathology
Demyelinating Autoimmune Diseases, CNS physiopathology
Demyelinating Diseases microbiology
Demyelinating Diseases pathology
Demyelinating Diseases physiopathology
Encephalomyelitis, Acute Disseminated immunology
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Plasmapheresis
Spinal Cord immunology
Steroids therapeutic use
Treatment Outcome
Brain microbiology
Brain pathology
Encephalomyelitis, Acute Disseminated microbiology
Encephalomyelitis, Acute Disseminated pathology
Legionnaires' Disease complications
Spinal Cord microbiology
Spinal Cord pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1538-3687
- Volume :
- 67
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Archives of neurology
- Publication Type :
- Academic Journal
- Accession number :
- 20457963
- Full Text :
- https://doi.org/10.1001/archneurol.2010.75