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Effect of diltiazem, a moderate CYP3A inhibitor, on the pharmacokinetics of anacetrapib, a potent cholesteryl ester transfer protein inhibitor, in healthy subjects.
- Source :
-
Journal of clinical pharmacology [J Clin Pharmacol] 2011 Mar; Vol. 51 (3), pp. 436-9. Date of Electronic Publication: 2010 Apr 23. - Publication Year :
- 2011
- Subjects :
- Adolescent
Adult
Delayed-Action Preparations
Diltiazem administration & dosage
Diltiazem adverse effects
Drug Interactions
Enzyme Inhibitors administration & dosage
Enzyme Inhibitors adverse effects
Female
Half-Life
Humans
Hyperlipidemias drug therapy
Linear Models
Male
Middle Aged
Oxazolidinones adverse effects
Oxazolidinones blood
Young Adult
Cholesterol Ester Transfer Proteins antagonists & inhibitors
Cytochrome P-450 CYP3A Inhibitors
Diltiazem pharmacology
Enzyme Inhibitors pharmacology
Oxazolidinones pharmacokinetics
Subjects
Details
- Language :
- English
- ISSN :
- 1552-4604
- Volume :
- 51
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of clinical pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 20418508
- Full Text :
- https://doi.org/10.1177/0091270010368676