Back to Search
Start Over
Myofibroblastic fibrosarcoma with multifocal osseous metaplasia at the site of equine influenza vaccination.
- Source :
-
Australian veterinary journal [Aust Vet J] 2010 Apr; Vol. 88 (4), pp. 132-6. - Publication Year :
- 2010
-
Abstract
- We describe a fibrosarcoma in a 12-year-old Quarterhorse x Arabian gelding as a sequela to equine influenza vaccination. Shortly after the second vaccination, swelling at the site was noticed by the owner and it continued to increase in size over the following 6 months. Biopsy of the mass indicated a fibrosarcoma had developed at the vaccination site. It was approximately 20 cm in diameter and elevated well above the level of the skin. There was no clinical evidence of metastases to the lungs or local lymph nodes. Surgical resection of the mass was performed and the wound healed by first and second intention. Histopathological examination and immunohistochemical staining confirmed a myofibroblastic fibrosarcoma with multifocal osseous metaplasia. To the authors' knowledge, this is the first equine case of a vaccine-associated fibrosarcoma.
- Subjects :
- Animals
Fibrosarcoma chemically induced
Fibrosarcoma surgery
Horse Diseases surgery
Horses
Male
Neoplasms, Muscle Tissue chemically induced
Neoplasms, Muscle Tissue surgery
Soft Tissue Neoplasms chemically induced
Soft Tissue Neoplasms surgery
Treatment Outcome
Vaccination adverse effects
Vaccination veterinary
Fibrosarcoma veterinary
Horse Diseases chemically induced
Influenza Vaccines adverse effects
Neoplasms, Muscle Tissue veterinary
Soft Tissue Neoplasms veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1751-0813
- Volume :
- 88
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Australian veterinary journal
- Publication Type :
- Academic Journal
- Accession number :
- 20402700
- Full Text :
- https://doi.org/10.1111/j.1751-0813.2010.00557.x