Relapsed diffuse large B-cell lymphoma treated by reduced-intensity allogeneic stem cell transplantation with donor lymphocyte infusion.

Authors :: Chaudhry QU
Ahmed P
Ullah K
Satti TM
Raza S
Mehmood SK
Akram M
Ahmed S
Source :: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2010 Mar; Vol. 20 (3), pp. 211-3.
Publication Year :: 2010
Abstract: A 42 years old male with relapsed diffuse large B-cell lymphoma was given second-line chemotherapy followed by reduced intensity allogeneic stem cell transplantation from HLA matched brother. Twelve weeks posttransplant, his disease relapsed evidenced by the appearance of lymphoma cells in the peripheral blood and declining donor chimerism. Donor lymphocyte infusion was given that induced complete lymphoma remission. The patient is well 3 years posttransplant with his disease in complete remission.

Subjects :: Adult
Antibodies, Monoclonal therapeutic use
Antibodies, Monoclonal, Humanized
Daclizumab
Graft vs Host Disease drug therapy
Humans
Immunoglobulin G therapeutic use
Immunosuppressive Agents therapeutic use
Male
Remission Induction
Hematopoietic Stem Cell Transplantation methods
Lymphocyte Transfusion
Lymphoma, B-Cell surgery
Transplantation Conditioning methods

Language :: English
ISSN :: 1022-386X
Volume :: 20
Issue :: 3
Database :: MEDLINE
Journal :: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Publication Type :: Academic Journal
Accession number :: 20392389
Full Text :: https://doi.org/03.2010/JCPSP.211213

Full Text Access

Tools