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[Crohn's disease: genetic aspects].

Authors :
Loranskaia ID
Stepanova EV
Source :
Terapevticheskii arkhiv [Ter Arkh] 2010; Vol. 82 (2), pp. 66-70.
Publication Year :
2010

Abstract

The paper deals with the topical problem of modern gastroenterology and coloproctology--the influence of genetic factors on the development and course of Crohn's disease (CD). It presents the data of foreign authors and the results of Russia 's first study evaluating the effect of the major polymorphic variants of the NOD2/CARD15 gene predisposing to CD on the risk, course, and other features of CD.

Subjects

Subjects :
Crohn Disease epidemiology
Crohn Disease metabolism
Humans
Morbidity
Russia
Crohn Disease genetics
DNA genetics
Genetic Predisposition to Disease
Nod2 Signaling Adaptor Protein genetics
Polymorphism, Genetic

Details

Language :
Russian
ISSN :
0040-3660
Volume :
82
Issue :
2
Database :
MEDLINE
Journal :
Terapevticheskii arkhiv
Publication Type :
Academic Journal
Accession number :
20387682

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