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Liver retransplantation in children: the Atlanta experience.
- Source :
-
Pediatric transplantation [Pediatr Transplant] 2010 May; Vol. 14 (3), pp. 417-25. Date of Electronic Publication: 2010 Mar 09. - Publication Year :
- 2010
-
Abstract
- Liver retransplantation is routinely offered at our institution. Previous reports document that patient and graft survival is significantly less after pediatric rLT compared to primary LT. This has engendered intense debate regarding optimal allocation of organs. Here, we examine our program's approach to pediatric hepatic retransplantation related to patient factors affecting outcomes. Between 1997 and 2009, 272 LTs were performed in 234 patients (mean survival 1994 +/- 1367 days) at our center. Thirty-four patients required rLT including 10 who received their primary transplant elsewhere and four who required two retransplantations. Patient survival did not differ significantly between rLT and LT at one and three yr (p = 0.56). Graft survival between rLT and LT was also similar (p = 0.606) at one and three yr. No significant difference in graft or patient survival was noted between: Patients retransplanted <30 days after LT vs. those >30 days (p = 0.152); patients transplanted with technical variants vs. whole grafts (p = 0.966); technical variants utilized for LT vs. rLT (p = 0.713); rLT recipient age (< or >5 yr; p = 0.298); or ABOI for rLT and LT (p = 0.650). Retransplantation should be offered to optimize pediatric recipient survival after LT and offers similar survival as primary transplant.
- Subjects :
- Adolescent
Chi-Square Distribution
Child
Child, Preschool
Female
Georgia epidemiology
Graft Rejection
Graft Survival
Humans
Infant
Liver Function Tests
Male
Postoperative Complications epidemiology
Reoperation statistics & numerical data
Risk Factors
Survival Analysis
Liver Transplantation
Outcome Assessment, Health Care
Subjects
Details
- Language :
- English
- ISSN :
- 1399-3046
- Volume :
- 14
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Pediatric transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 20331514
- Full Text :
- https://doi.org/10.1111/j.1399-3046.2010.01304.x