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Photoreversible DNA end capping for the formation of hairpin structures.

Authors :
Yoshimura Y
Okada H
Fujimoto K
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2010 Apr 07; Vol. 8 (7), pp. 1523-6. Date of Electronic Publication: 2010 Feb 17.
Publication Year :
2010

Abstract

We describe a photoreversible DNA end capping via 3-cyanovinylcarbazole nucleoside. Doubly end-capped oligodeoxynucleotide (ODN) exhibits increased stability against snake venom phosphodiesterase and shows high thermal stability.

Subjects

Subjects :
Cross-Linking Reagents metabolism
Nucleic Acid Conformation
Oligodeoxyribonucleotides metabolism
Phosphodiesterase I metabolism
Photochemistry
Snake Venoms metabolism
Temperature
Cross-Linking Reagents chemistry
DNA chemistry
DNA metabolism
Oligodeoxyribonucleotides chemistry

Details

Language :
English
ISSN :
1477-0539
Volume :
8
Issue :
7
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
20237661
Full Text :
https://doi.org/10.1039/b924989c
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