Angiogenic imbalances: the obstetric perspective.

Authors :: Espinoza J
Uckele JE
Starr RA
Seubert DE
Espinoza AF
Berry SM
Source :: American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2010 Jul; Vol. 203 (1), pp. 17.e1-8. Date of Electronic Publication: 2010 Mar 15.
Publication Year :: 2010
Abstract: Clinical and experimental evidence indicates that angiogenic imbalances may participate in the mechanisms of disease of several pregnancy complications, some of which may be life threatening. This article reviews current evidence in support of this view and the possibility that the fetus may play a central role in these imbalances; it also reviews recent experimental observations that modulation of angiogenic imbalances during pregnancy may have prophylactic and/or therapeutic value.<br /> (Copyright (c) 2010 Mosby, Inc. All rights reserved.)