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[In vitro investigation of Ingavirin efficacy against influenza B virus].

Authors :
Loginova SIa
Borisevich SV
Semenova IA
Borisevich GV
Maksimov VA
Bondarev VP
Nebol'sin VE
Source :
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 2009; Vol. 54 (7-8), pp. 13-5.
Publication Year :
2009

Abstract

The experimental investigation of Ingavirin activity against influenza B virus showed that in concentrations 100 and 200 mcg/ml it was efficient in inhibition of the virus reproduction: the cytopathic effect was lowered by 75%, the level of the pathogen accumulation in the MDCK cell culture was decreased by more than 2.0 lg and the formation of the virus specific hemagglutinin was inhibited by more than 90%.

Subjects

Subjects :
Animals
Caproates
Cell Line
Cytopathogenic Effect, Viral drug effects
Dogs
Hemagglutinin Glycoproteins, Influenza Virus biosynthesis
Influenza B virus physiology
Virus Replication drug effects
Amides pharmacology
Antiviral Agents pharmacology
Dicarboxylic Acids pharmacology
Imidazoles pharmacology
Influenza B virus drug effects

Details

Language :
Russian
ISSN :
0235-2990
Volume :
54
Issue :
7-8
Database :
MEDLINE
Journal :
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]
Publication Type :
Academic Journal
Accession number :
20201397

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Authors Abstract Subjects Details