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Limb salvage for soft-tissue sarcomas of the foot and ankle.
- Source :
-
The Journal of bone and joint surgery. British volume [J Bone Joint Surg Br] 2010 Mar; Vol. 92 (3), pp. 424-9. - Publication Year :
- 2010
-
Abstract
- We evaluated the oncological and functional outcome of 27 patients who had limb salvage for a soft-tissue sarcoma of the foot or ankle between 1992 and 2007, with a mean follow-up of 7.5 years (1.05 to 16.2). There were 12 men and 15 women, with a mean age at presentation of 47 years (12 to 84). Referrals came from other hospitals for 16 patients who had previous biopsy or unplanned excision, and 11 presented de novo. There were 18 tumours located in the foot and nine around the ankle. Synovial sarcoma was the most frequent histological diagnosis. Excision was performed in all cases, with 16 patients requiring plastic surgical reconstruction with 13 free and three local flaps. Adjuvant treatment was undertaken in 20 patients, 18 with radiotherapy and two by chemotherapy. Limb salvage was successful in 26 of the 27 patients. There have been two local recurrences and two mesenchymal metastases. Four patients have died of their sarcoma and two of other causes. Function was evaluated with the Toronto Extremity Salvage Score and a mean overall score of 89.40 (52.1 to 100) was obtained. A questionnaire revealed that all surviving patients are able to wear normal shoes and none require a walking aid. Limb salvage can achieve good oncological and functional results with additional treatment.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Child
Combined Modality Therapy
Female
Follow-Up Studies
Foot Diseases rehabilitation
Humans
Limb Salvage rehabilitation
Male
Middle Aged
Postoperative Complications
Plastic Surgery Procedures methods
Recovery of Function
Sarcoma rehabilitation
Soft Tissue Neoplasms rehabilitation
Surgical Flaps
Survival Analysis
Treatment Outcome
Young Adult
Ankle
Foot Diseases therapy
Limb Salvage methods
Sarcoma therapy
Soft Tissue Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2044-5377
- Volume :
- 92
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Journal of bone and joint surgery. British volume
- Publication Type :
- Academic Journal
- Accession number :
- 20190316
- Full Text :
- https://doi.org/10.1302/0301-620X.92B3.22331