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Impact of the new lung cancer staging system for a predominantly advanced-disease patient population.
- Source :
-
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2010 Mar; Vol. 5 (3), pp. 340-3. - Publication Year :
- 2010
-
Abstract
- Introduction: To investigate the feasibility and clinical impact of the 7th edition of the "Tumor, Node, Metastasis" (TNM) classification scheme in lung cancer as proposed by the International Association for the Study of Lung Cancer (IASLC) for non-small cell lung cancer.<br />Methods: We evaluated the feasibility of the new staging system in our routine biweekly multidisciplinary lung cancer staging conference compared with the 6th TNM staging in a prospective manner from April 2008 to June 2009. The impact of IASLC staging versus the 6th TNM staging was observed at three levels: change in substaging, staging, and clinical management (based on the discussion within the staging conference).<br />Results: From 348 patients discussed during these conferences, 226 eligible non-small cell lung cancer patients newly diagnosed within the study period were reviewed and clinically staged. The majority were elderly (median age, 67 years) and men (58%). Of these, 23 patients had different staging, and four patients had different substaging in the IASLC staging compared with the 6th TNM staging. An impact on clinical management was seen in 2.7% (6 of 226) of these patients because of coding ipsilateral different-lobe metastasis as T4 instead of M1.<br />Conclusions: The new staging system was clinically feasible and resulted in some (27 of 226, 12%) differences in staging. An impact on clinical decision making was occasionally seen within our institutional practice. Further studies are needed to investigate the comprehensive and long-term impact of the new staging system.
- Subjects :
- Adenocarcinoma classification
Adenocarcinoma surgery
Adult
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung classification
Carcinoma, Non-Small-Cell Lung surgery
Carcinoma, Squamous Cell classification
Carcinoma, Squamous Cell surgery
Feasibility Studies
Female
Humans
Lung Neoplasms classification
Lung Neoplasms surgery
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Invasiveness
Neoplasm Staging
Prognosis
Prospective Studies
Survival Rate
Adenocarcinoma pathology
Carcinoma, Non-Small-Cell Lung pathology
Carcinoma, Squamous Cell pathology
Lung Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1556-1380
- Volume :
- 5
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 20186024
- Full Text :
- https://doi.org/10.1097/JTO.0b013e3181c8137a