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Incidental Lewy body disease: clinical comparison to a control cohort.
- Source :
-
Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2010 Apr 15; Vol. 25 (5), pp. 642-6. - Publication Year :
- 2010
-
Abstract
- Limited clinical information has been published on cases pathologically diagnosed with incidental Lewy body disease (ILBD). Standardized, longitudinal movement and cognitive data was collected on a cohort of subjects enrolled in the Sun Health Research Institute Brain and Body Donation Program. Of 277 autopsied subjects who had antemortem clinical evaluations within the previous 3 years, 76 did not have Parkinson's disease, a related disorder, or dementia of which 15 (20%) had ILBD. Minor extrapyramidal signs were common in subjects with and without ILBD. Cognitive testing revealed an abnormality in the ILBD group in the Trails B test only. ILBD cases had olfactory dysfunction; however, sample size was very small. This preliminary report revealed ILBD cases have movement and cognitive findings that for the most part were not out of proportion to similarly assessed and age-similar cases without Lewy bodies. Larger sample size is needed to have the power to better assess group differences.<br /> ((c) 2010 Movement Disorder Society.)
- Subjects :
- Aged
Aged, 80 and over
Cohort Studies
Disability Evaluation
Female
Humans
Lewy Body Disease physiopathology
Male
Neuropsychological Tests
Olfaction Disorders diagnosis
Parkinson Disease physiopathology
Retrospective Studies
Severity of Illness Index
Lewy Body Disease diagnosis
Parkinson Disease diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1531-8257
- Volume :
- 25
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Movement disorders : official journal of the Movement Disorder Society
- Publication Type :
- Academic Journal
- Accession number :
- 20175211
- Full Text :
- https://doi.org/10.1002/mds.22971