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A detailed investigation of the aza-Prins reaction.
- Source :
-
Organic & biomolecular chemistry [Org Biomol Chem] 2010 Mar 07; Vol. 8 (5), pp. 1064-80. Date of Electronic Publication: 2010 Jan 05. - Publication Year :
- 2010
-
Abstract
- The development of a Lewis acid-promoted aza-Prins reaction to form piperidines and pyrrolidines is described. Indium trichloride has been found to be a highly successful and mild Lewis acid for promoting this reaction. A thorough mechanistic investigation is described, including the factors that influence the formation of the 5- or 6-membered ring product(s).
Details
- Language :
- English
- ISSN :
- 1477-0539
- Volume :
- 8
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Organic & biomolecular chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 20165797
- Full Text :
- https://doi.org/10.1039/b915797b