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Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii.
- Source :
-
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2010 Mar 15; Vol. 20 (6), pp. 2021-4. Date of Electronic Publication: 2010 Jan 20. - Publication Year :
- 2010
-
Abstract
- A new bisindole alkaloid, bisleuconothine A (1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A (1) showed cell growth inhibitory activity against various human cancer cell lines.<br /> (Copyright 2010 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1464-3405
- Volume :
- 20
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry letters
- Publication Type :
- Academic Journal
- Accession number :
- 20153644
- Full Text :
- https://doi.org/10.1016/j.bmcl.2010.01.051