[Activity of calpaines in spinal cord cells of the rats with experimental allergic encephalomyelitis of different grades].

Authors :: Karpenko MN
Abdurasulova IN
Klimenko VM
Source :: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2009 Dec; Vol. 95 (12), pp. 1407-15.
Publication Year :: 2009
Abstract: In simulation of experimental allergic encephalomyelitis (EAE), a hyperactivation of calpaines occurs due to m-calpaines. The m-calpaines involvement in the process of initiation of neurons and glial cells death in the EAE development was suggested.

Subjects :: Animals
Cell Death
Encephalomyelitis, Autoimmune, Experimental pathology
Female
Neuroglia pathology
Neurons pathology
Rats
Rats, Wistar
Spinal Cord pathology
Calpain metabolism
Encephalomyelitis, Autoimmune, Experimental enzymology
Neuroglia enzymology
Neurons enzymology
Spinal Cord enzymology

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