The synergistic efficacy of adalimumab and pamidronate in a patient with ankylosing spondylitis.

Authors :: Slobodin G
Rosner I
Rimar D
Boulman N
Rozenbaum M
Odeh M
Source :: Clinical rheumatology [Clin Rheumatol] 2010 Jul; Vol. 29 (7), pp. 793-4. Date of Electronic Publication: 2010 Jan 29.
Publication Year :: 2010
Abstract: A patient with ankylosing spondylitis, after demonstrating incomplete clinical response to adalimumab, received three monthly infusions of pamidronate along with continuing TNF-alpha blockade. Complete disappearance of the back pain was reported after the second pamidronate infusion. The perspectives of the combination therapy with TNF-alpha inhibitor and pamidronate are discussed.

Subjects :: Adalimumab
Antibodies, Monoclonal, Humanized
Drug Synergism
Drug Therapy, Combination
Female
Humans
Middle Aged
Pamidronate
Treatment Outcome
Anti-Inflammatory Agents therapeutic use
Antibodies, Monoclonal therapeutic use
Diphosphonates therapeutic use
Spondylitis, Ankylosing drug therapy

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