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Successful treatment of life-threatening Candida peritonitis in a child with abdominal non-Hodgkin lymphoma using Efungumab and amphotericin B colloid dispersion.

Authors :
Krenova Z
Pavelka Z
Lokaj P
Skotakova J
Kocmanova I
Teyschl O
Kren L
Mudry P
Sterba J
Source :
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2010 Mar; Vol. 32 (2), pp. 128-30.
Publication Year :
2010

Abstract

Invasive fungal infections are serious complications of cancer therapy. We present a case report of a 12-year-old boy diagnosed with abdominal non-Hodgkin lymphoma and fecal and Candida peritonitis during induction chemotherapy. The invasive mycosis was managed using a combined approach of systemic antifungal agents including efungumab and surgical interventions. Efungumab, a recombinant antibody that inhibits extracellular heat shock protein 90, was used in combination with amphotericin B colloid dispersion after the failure of standard approaches.

Details

Language :
English
ISSN :
1536-3678
Volume :
32
Issue :
2
Database :
MEDLINE
Journal :
Journal of pediatric hematology/oncology
Publication Type :
Academic Journal
Accession number :
20098335
Full Text :
https://doi.org/10.1097/MPH.0b013e3181cb49a8