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[Evaluation of the protocol CMA reinforced in the treatment of endemic Burkitt lymphoma at CHU of Yopougon in Abidjan].
- Source :
-
Bulletin du cancer [Bull Cancer] 2010 May; Vol. 97 (5), pp. 507-9. - Publication Year :
- 2010
-
Abstract
- We report the results of the protocol CMA (cyclophosphamide, methotrexate, Aracytine) reinforced of 26 patients affected by Burkitt lymphoma in facial-maxillary localisation, in a retrospective study from January 2000 till December 2007 and prospective from January till September 2008. Their average age was 7.89 years, with a sex ratio of 2.71. The global response to the treatment was 92.3% with 57.7% of complete remission and 34.6% of incomplete remission. The morbidity related to treatment was essentially a haematological complication (84.6%) and hydroelectrolytic complication (84.6%). Evolution was made towards death in 30.8 and 15.4% were lost of view. The median monitoring was 18.2 months. Treatment response was linked to the therapeutic compliance (P < 0.001), and the delay of consultation (P = 0.01).
- Subjects :
- Burkitt Lymphoma pathology
Child
Child, Preschool
Cote d'Ivoire
Cyclophosphamide administration & dosage
Cytarabine administration & dosage
Facial Neoplasms pathology
Female
Humans
Infant
Infant, Newborn
Male
Maxillary Neoplasms pathology
Methotrexate administration & dosage
Remission Induction
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Burkitt Lymphoma drug therapy
Facial Neoplasms drug therapy
Maxillary Neoplasms drug therapy
Subjects
Details
- Language :
- French
- ISSN :
- 1769-6917
- Volume :
- 97
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Bulletin du cancer
- Publication Type :
- Academic Journal
- Accession number :
- 20071300
- Full Text :
- https://doi.org/10.1684/bdc.2010.1037