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Small molecule induced control in duplex and triplex DNA-directed chemical reactions.

Authors :
Jacobsen MF
Ravnsbaek JB
Gothelf KV
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2010 Jan 07; Vol. 8 (1), pp. 50-2. Date of Electronic Publication: 2009 Nov 09.
Publication Year :
2010

Abstract

Triplex DNA binders can effectively control copper-catalysed alkyne-azide click reactions in DNA architecture, such that either duplex or triplex DNA directed reactions of terminally attached azides and alkynes occur, in the absence or presence of triplex DNA binder, respectively.

Details

Language :
English
ISSN :
1477-0539
Volume :
8
Issue :
1
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
20024130
Full Text :
https://doi.org/10.1039/b919387a