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Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies.
Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies.
- Source :
-
BMC infectious diseases [BMC Infect Dis] 2009 Dec 10; Vol. 9, pp. 200. Date of Electronic Publication: 2009 Dec 10. - Publication Year :
- 2009
-
Abstract
- Background: Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood.<br />Case Presentation: We report the first case of CHIKV infection with chronic associated rheumatism in a patient who developed progressive erosive arthritis with expression of inflammatory mediators and persistence of specific IgM antibodies over 24 months following infection.<br />Conclusions: Understanding the specific features of chikungunya virus as well as how the virus interacts with its host are essential for the prevention, treatment or cure of chikungunya disease.
Details
- Language :
- English
- ISSN :
- 1471-2334
- Volume :
- 9
- Database :
- MEDLINE
- Journal :
- BMC infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 20003320
- Full Text :
- https://doi.org/10.1186/1471-2334-9-200