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Report of varicella outbreak in a low vaccination coverage group of otherwise healthy children in Italy: the role of breakthrough and the need of a second dose of vaccine.
- Source :
-
Vaccine [Vaccine] 2010 Feb 10; Vol. 28 (6), pp. 1594-7. Date of Electronic Publication: 2009 Dec 02. - Publication Year :
- 2010
-
Abstract
- We describe an outbreak of varicella at a preschool center in Southern Italy, in the period January-May 2009, among children with a vaccination coverage of 53.9% for one dose. The outbreak occurred in a small community in Puglia and enrolled 41 children. The attack rates for unvaccinated and vaccinated children were 72.3% and 12.7%, respectively. The vaccine effectiveness against disease was 82.4%. Our findings add a further piece of evidence in supporting the routine use of a second dose of vaccine for all children without a history of disease, as recently recommended by the ACIP of the CDC.<br /> (Copyright (c) 2009 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1873-2518
- Volume :
- 28
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Vaccine
- Publication Type :
- Academic Journal
- Accession number :
- 19961965
- Full Text :
- https://doi.org/10.1016/j.vaccine.2009.11.047