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Validity of the California Verbal Learning Test-II in multiple sclerosis.
- Source :
-
The Clinical neuropsychologist [Clin Neuropsychol] 2010 Feb; Vol. 24 (2), pp. 189-202. Date of Electronic Publication: 2009 Nov 26. - Publication Year :
- 2010
-
Abstract
- Multiple sclerosis (MS) is a disease of the central nervous system where roughly 50% of patients exhibit cognitive impairment. Episodic memory defects are particularly common in MS and the California Verbal Learning Test: 2nd Edition (CVLT-II) was recommended for assessment in MS in a recently published consensus position paper. We investigated the validity of the CVLT-II in 351 MS patients and 69 demographically matched normal controls. MS patients performed significantly more poorly on 18 of the 23 measures examined. In addition to a general memory factor, factor analysis revealed five distinct factors conforming to measures of consolidation, primary/recency effect, proactive interference, and learning asymptote. The external validity of the CVLT-II was also supported by logistic regression analysis, which separated employed from work-disabled MS patients. We conclude that the CVLT-II is a valid test in MS and provides a rich constellation of verbal memory measures.
Details
- Language :
- English
- ISSN :
- 1744-4144
- Volume :
- 24
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The Clinical neuropsychologist
- Publication Type :
- Academic Journal
- Accession number :
- 19953426
- Full Text :
- https://doi.org/10.1080/13854040903266910