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Characterisation of G8 human rotaviruses in Australian children with gastroenteritis.
- Source :
-
Virus research [Virus Res] 2010 Mar; Vol. 148 (1-2), pp. 1-7. Date of Electronic Publication: 2009 Dec 03. - Publication Year :
- 2010
-
Abstract
- This study describes the characterisation of G8 rotavirus strains isolated from humans with acute gastroenteritis. Six G8 strains were detected in Australia between 2002 and 2008. Four were G8P[14] strains, one was G8P[8]+[14] and one was G8 P non-typeable. By polyacrylamide gel electrophoresis and enzyme immunoassay analysis, four G8 strains with visible RNA exhibited a long electropherotype and five G8 strains displayed subgroup I specificity. Sequence analysis of the VP7 gene indicated that the G8 strains exhibited the highest nucleotide and amino acid identity with a G8P[11] bovine rotavirus strain detected in Japan. VP4 sequence data of one G8P[14] strain revealed that the closest identity was to another human-bovine-like strain detected in Australia, MG6, a G6P[14] strain. The identification of G8 strains causing disease further extends the number of G8P[14] strains detected in Australian children, and indicates that there is a rare but ongoing presence of uncommon human strains within the community in Australia.<br /> (Copyright 2009 Elsevier B.V. All rights reserved.)
- Subjects :
- Amino Acid Sequence
Australia epidemiology
Child
Female
Gastroenteritis epidemiology
Humans
Male
Molecular Sequence Data
Phylogeny
Rotavirus chemistry
Rotavirus genetics
Sequence Alignment
Viral Proteins chemistry
Viral Proteins genetics
Gastroenteritis virology
Rotavirus classification
Rotavirus isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7492
- Volume :
- 148
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Virus research
- Publication Type :
- Academic Journal
- Accession number :
- 19948195
- Full Text :
- https://doi.org/10.1016/j.virusres.2009.11.013