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Laparoscopic procurement of single versus multiple artery kidney allografts: is long-term graft survival affected?
- Source :
-
Transplantation [Transplantation] 2009 Nov 27; Vol. 88 (10), pp. 1203-7. - Publication Year :
- 2009
-
Abstract
- Background: Living donor kidneys with multiple arteries (MA) are increasingly procured laparoscopically for transplant.<br />Methods: We compare long-term graft function and survival of kidneys with single arteries (SA) and MA over a 10-year period.<br />Results: There were a total of 218 grafts with SA and 60 grafts with MA. The MA group had longer operative and ischemic times than SA group. There was a small increase in ureteral complication (8.3% vs. 2.3% P=0.06) and a significantly higher incidence of rejection (23.3% vs. 10.1%, P=0.01) in MA group than in SA group. Graft function was lower in MA group than SA group. The 5-year graft survival by Kaplan Meier analysis was better in SA group than in MA group (P=0.023). The estimated graft survivals at 1, 3, and 5 year were 94.4%, 90.6%, and 86% for SA group and 89.6%, 83.2%, and 71.8% for MA group. There was a higher percentage of graft loss from chronic allograft nephropathy in MA group than in SA group (16.7% vs. 5.5%, P=0.01). The presence of MA (vs. SA) was an independent risk for acute rejection (OR 3.60, 95% CI 1.59-8.14, P=0.002) and for graft loss (HR 2.31, 95% CI 1.05-5.09, P=0.038).<br />Conclusion: Laparoscopic procurement of living donor kidneys with SA may be associated with a lower risk of rejection, better function, and superior long-term survival when compared with kidneys with MA.
- Subjects :
- Adult
Follow-Up Studies
Graft Rejection epidemiology
Graft Survival immunology
Humans
Incidence
Kidney Failure, Chronic etiology
Kidney Transplantation immunology
Kidney Transplantation mortality
Middle Aged
Renal Artery abnormalities
Retrospective Studies
Surgical Procedures, Operative methods
Survival Rate
Survivors
Time Factors
Treatment Failure
Treatment Outcome
Young Adult
Graft Survival physiology
Kidney Transplantation physiology
Laparoscopy methods
Nephrectomy methods
Renal Artery surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1534-6080
- Volume :
- 88
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 19935374
- Full Text :
- https://doi.org/10.1097/TP.0b013e3181ba343a