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Effective desensitization to imiglucerase in a patient with type I Gaucher disease.
- Source :
-
The Journal of pediatrics [J Pediatr] 2009 Dec; Vol. 155 (6), pp. 940-1. - Publication Year :
- 2009
-
Abstract
- We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date.
- Subjects :
- Anaphylaxis chemically induced
Anaphylaxis diagnosis
Child
Drug Hypersensitivity diagnosis
Drug Hypersensitivity etiology
Gaucher Disease immunology
Glucosylceramidase adverse effects
Humans
Male
Anaphylaxis therapy
Desensitization, Immunologic
Drug Hypersensitivity therapy
Gaucher Disease drug therapy
Glucosylceramidase administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1097-6833
- Volume :
- 155
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The Journal of pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 19914435
- Full Text :
- https://doi.org/10.1016/j.jpeds.2009.05.033