Back to Search
Start Over
Clinical outcome of tailored adjuvant postoperative chemoradiotherapy in IB FIGO stage cervical cancer.
- Source :
-
Anticancer research [Anticancer Res] 2009 Oct; Vol. 29 (10), pp. 4205-10. - Publication Year :
- 2009
-
Abstract
- Aim: The aim of the present report is to review a mono-institutional experience of postoperative radiotherapy in selected patients with cervical cancer.<br />Patients and Methods: Between 1999 and 2008, fifty-one patients with high-risk stage IB cervical cancer underwent tailored adjuvant postoperative radiotherapy; concurrent chemoradiotherapy was administered to patients presenting a high risk of recurrence. The median follow-up was 58 months.<br />Results: All patients were in complete remission at first follow-up assessment. Ten patients were subject to recurrences between 7 and 54 months after treatment. The 2-year and 5-year disease-free survival rates were 88.1% and 74.9%, respectively; 2-year and 5-year overall survival rates of the whole group were 91.8% and 82.0%, respectively. Only one case of grade 4 and four cases of grade 3 side effects were reported.<br />Conclusion: Tailored adjuvant postoperative chemoradiotherapy is able to obtain a satisfactory clinical outcome in patients with high-risk early-stage IB cervical cancer.
- Subjects :
- Adult
Aged
Aged, 80 and over
Brachytherapy
Chemotherapy, Adjuvant
Disease-Free Survival
Female
Humans
Middle Aged
Neoplasm Staging
Postoperative Care
Radiotherapy, Adjuvant
Retrospective Studies
Treatment Outcome
Uterine Cervical Neoplasms pathology
Uterine Cervical Neoplasms surgery
Uterine Cervical Neoplasms drug therapy
Uterine Cervical Neoplasms radiotherapy
Subjects
Details
- Language :
- English
- ISSN :
- 1791-7530
- Volume :
- 29
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Anticancer research
- Publication Type :
- Academic Journal
- Accession number :
- 19846974