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[Donation after cardiac death: cardiac arrest during donor maintenance after brain death].
- Source :
-
Medicina intensiva [Med Intensiva] 2009 Oct; Vol. 33 (7), pp. 327-35. Date of Electronic Publication: 2009 Sep 17. - Publication Year :
- 2009
-
Abstract
- Brain death implies the complete cessation of activity in both cerebral hemispheres and in the brainstem; this leads to severe physiopathological disorders that make donor maintenance complex and involve the concomitant risk of rapid organ deterioration. The heart is one of the target organs in this process of multiple organ failure. Myocardial stunning occurs due to a "catecholamine storm" and subsequent release of many proinflammatory mediators, free oxygen radicals, and electrolyte imbalance secondary to insipid diabetes and hypothermia. Cardiac arrest during the maintenance of a donor after brain death is relatively frequent. The shortage of organs for transplantation has led to the broadening of the criteria for organ donation to include donation after cardiac death or non heart beating donation, among others.
- Subjects :
- Death
Humans
Brain Death
Death, Sudden, Cardiac
Tissue Donors classification
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0210-5691
- Volume :
- 33
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Medicina intensiva
- Publication Type :
- Academic Journal
- Accession number :
- 19828395
- Full Text :
- https://doi.org/10.1016/j.medin.2008.12.003