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[Donation after cardiac death: cardiac arrest during donor maintenance after brain death].

Authors :
del Río-Gallegos F
Escalante-Cobo JL
Núñez-Peña JR
Calvo-Manuel E
Source :
Medicina intensiva [Med Intensiva] 2009 Oct; Vol. 33 (7), pp. 327-35. Date of Electronic Publication: 2009 Sep 17.
Publication Year :
2009

Abstract

Brain death implies the complete cessation of activity in both cerebral hemispheres and in the brainstem; this leads to severe physiopathological disorders that make donor maintenance complex and involve the concomitant risk of rapid organ deterioration. The heart is one of the target organs in this process of multiple organ failure. Myocardial stunning occurs due to a "catecholamine storm" and subsequent release of many proinflammatory mediators, free oxygen radicals, and electrolyte imbalance secondary to insipid diabetes and hypothermia. Cardiac arrest during the maintenance of a donor after brain death is relatively frequent. The shortage of organs for transplantation has led to the broadening of the criteria for organ donation to include donation after cardiac death or non heart beating donation, among others.

Details

Language :
Spanish; Castilian
ISSN :
0210-5691
Volume :
33
Issue :
7
Database :
MEDLINE
Journal :
Medicina intensiva
Publication Type :
Academic Journal
Accession number :
19828395
Full Text :
https://doi.org/10.1016/j.medin.2008.12.003