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[Apoptosis of mononuclear cells and dead leukocytes in venous blood of septic patients].
- Source :
-
Vestnik Rossiiskoi akademii meditsinskikh nauk [Vestn Ross Akad Med Nauk] 2009 (8), pp. 33-6. - Publication Year :
- 2009
-
Abstract
- Apoptosis of mononuclear cells, dead leukocyte and CD95+ lymphocytes content in venous blood of 15 patients were evaluated by flow cytometry within 2-3 day after diagnosis of sepsis. The number of CD95+ lymphocytes increased in 40% of the cases and that of lymphocytes expressing Fas receptor decreased in 27%. The number of mononuclear cells in venous blood increased 7 times compared with physiological norm; this rise was a reliable predictor of the unfavourable outcome of the disease. Elimination of dead leukocytes by granulocytophoresis produced good therapeutic result.
Details
- Language :
- Russian
- ISSN :
- 0869-6047
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Vestnik Rossiiskoi akademii meditsinskikh nauk
- Publication Type :
- Academic Journal
- Accession number :
- 19799211