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[The autotransplantation of hematopoietic stem cells from the peripheral blood].

Authors :
Aleksanian MZh
Ryzhko VV
Mkheidze DM
Gerasimova LP
Selezneva OM
Source :
Terapevticheskii arkhiv [Ter Arkh] 1990; Vol. 62 (7), pp. 26-31.
Publication Year :
1990

Abstract

The authors discuss the existence of polypotent hemopoietic stem cells in the peripheral blood as well as a possibility of restoring hemopoiesis by means of the given cells after the lethal myelotoxic exposure. In 5 patients with hemoblastoses, suspension of mononuclear leukocytes in an amount of 0.5 X 10(9) per kg bw was obtained using short-interval leukocytapheresis on blood cell separator. After carrying out different schemes of pretransplantation preparation the defrosted suspension of mononuclear cells was injected without wash out to the patients' central vein. The recovery of the peripheral blood indicators was attained on days 10-30 after the autotransplantation of stem blood cells.

Details

Language :
Russian
ISSN :
0040-3660
Volume :
62
Issue :
7
Database :
MEDLINE
Journal :
Terapevticheskii arkhiv
Publication Type :
Academic Journal
Accession number :
1979189