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[The autotransplantation of hematopoietic stem cells from the peripheral blood].
- Source :
-
Terapevticheskii arkhiv [Ter Arkh] 1990; Vol. 62 (7), pp. 26-31. - Publication Year :
- 1990
-
Abstract
- The authors discuss the existence of polypotent hemopoietic stem cells in the peripheral blood as well as a possibility of restoring hemopoiesis by means of the given cells after the lethal myelotoxic exposure. In 5 patients with hemoblastoses, suspension of mononuclear leukocytes in an amount of 0.5 X 10(9) per kg bw was obtained using short-interval leukocytapheresis on blood cell separator. After carrying out different schemes of pretransplantation preparation the defrosted suspension of mononuclear cells was injected without wash out to the patients' central vein. The recovery of the peripheral blood indicators was attained on days 10-30 after the autotransplantation of stem blood cells.
- Subjects :
- Adolescent
Adult
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Colony-Forming Units Assay
Combined Modality Therapy
Female
Hodgkin Disease blood
Hodgkin Disease therapy
Humans
Leukapheresis methods
Leukemia, Myelomonocytic, Acute blood
Leukemia, Myelomonocytic, Acute therapy
Male
Middle Aged
Multiple Myeloma blood
Multiple Myeloma therapy
Transplantation, Autologous
Hematopoietic Stem Cell Transplantation
Subjects
Details
- Language :
- Russian
- ISSN :
- 0040-3660
- Volume :
- 62
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Terapevticheskii arkhiv
- Publication Type :
- Academic Journal
- Accession number :
- 1979189