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Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana.
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2009 Sep; Vol. 15 (9), pp. 1377-84. - Publication Year :
- 2009
-
Abstract
- We tested 12 bat species in Ghana for coronavirus (CoV) RNA. The virus prevalence in insectivorous bats (n = 123) was 9.76%. CoV was not detected in 212 fecal samples from Eidolon helvum fruit bats. Leaf-nosed bats pertaining to Hipposideros ruber by morphology had group 1 and group 2 CoVs. Virus concentrations were < or =45,000 copies/100 mg of bat feces. The diversified group 1 CoV shared a common ancestor with the human common cold virus hCoV-229E but not with hCoV-NL63, disputing hypotheses of common human descent. The most recent common ancestor of hCoV-229E and GhanaBt-CoVGrp1 existed in approximately 1686-1800 ad. The GhanaBt-CoVGrp2 shared an old ancestor (approximately 2,400 years) with the severe acute respiratory syndrome-like group of CoV.
- Subjects :
- Animals
Coronavirus 229E, Human genetics
Feces virology
Female
Ghana
Humans
Male
Molecular Sequence Data
Phylogeny
RNA, Viral analysis
RNA, Viral isolation & purification
RNA-Dependent RNA Polymerase genetics
Severe acute respiratory syndrome-related coronavirus genetics
Sequence Analysis, DNA
Chiroptera virology
Coronavirus classification
Coronavirus genetics
Coronavirus isolation & purification
Coronavirus 229E, Human classification
Severe acute respiratory syndrome-related coronavirus classification
Subjects
Details
- Language :
- English
- ISSN :
- 1080-6059
- Volume :
- 15
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 19788804
- Full Text :
- https://doi.org/10.3201/eid1509.090224