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Clinical characteristics of Behçet's disease in China.

Authors :
Wang LY
Zhao DB
Gu J
Dai SM
Source :
Rheumatology international [Rheumatol Int] 2010 Jul; Vol. 30 (9), pp. 1191-6. Date of Electronic Publication: 2009 Sep 24.
Publication Year :
2010

Abstract

To evaluate the prevalence of clinical findings in Behçet's disease (BD) in Chinese population. The clinical data of 170 consecutive BD patients were, retrospectively, analyzed and compared with previous reports. The mean age at onset was 34.4 years (range 6-72) and the mean age of diagnosis was 39.1 years (range 8-72). Mean delay in diagnosis was 5.7 years. The male to female ratio was 1.3:1. Recurrent aphthous ulceration (64.7%), skin lesion (18.2%), and genital ulceration (8.2%) were the commonest onset-presentations of the disease. During the disease course, the commonest presenting features were oral ulcer (100%), cutaneous involvement (68.2%), genital ulcer (63.5%), arthritis (37.1%), and ocular lesion (14.1%). As for the minor clinical manifestations, gastrointestinal lesion (10.0%), vascular lesion (8.8%), and cardiac lesion (4.7%) occurred occasionally. The pathergy skin test showed positive in 63.5% of the patients and revealed a higher positive rate in the females (76.7%) than in the males (53.6%). Less ocular lesion and genital ulcer were present in Chinese BD patients.

Details

Language :
English
ISSN :
1437-160X
Volume :
30
Issue :
9
Database :
MEDLINE
Journal :
Rheumatology international
Publication Type :
Academic Journal
Accession number :
19777242
Full Text :
https://doi.org/10.1007/s00296-009-1127-9