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Long-term follow-up after drug eluting stent implantation in left main trifurcations.
- Source :
-
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology [EuroIntervention] 2009 Sep; Vol. 5 (4), pp. 432-7. - Publication Year :
- 2009
-
Abstract
- Aims: Trifurcation lesions, which are mostly observed in distal left main (LM), represent a technical challenge for interventional cardiologists. We sought to determine the feasibility and long-term clinical outcome of drug eluting stent (DES) implantation in patients with LM coronary trifurcation lesions.<br />Methods and Results: All patients with clinically significant de novo LM trifurcation lesions, who refused coronary artery bypass surgery and were considered eligible for percutaneous coronary intervention (PCI), were consecutively enrolled in this study from November 2005 to February 2007. Eleven patients (65+/-9 years, 91% men) met all the inclusion criteria and underwent LM trifurcation stenting with DES. Angiographic success was 100%. Clinical follow-up in all patients and angiographic follow-up in 91% of patients was available at 32+/-7 and 8+/-2 months, respectively. The primary endpoint, defined as the composite of cardiac death or acute myocardial infarction, occurred in one patient (9%). No cases of stent thrombosis were recorded. Three patients (27%), experienced a clinically-driven target lesion revascularisation (TLR).<br />Conclusions: PCI with DES implantation in patients with LM trifurcation seems feasible and safe, with acceptable TLR rates. Large scale multicentre registries are warranted to reliably address clinical outcome of this subset of patients.
- Subjects :
- Aged
Coronary Angiography
Equipment Design
Female
Follow-Up Studies
Humans
Immunosuppressive Agents administration & dosage
Immunosuppressive Agents therapeutic use
Male
Middle Aged
Paclitaxel administration & dosage
Paclitaxel therapeutic use
Sirolimus administration & dosage
Sirolimus therapeutic use
Tubulin Modulators administration & dosage
Tubulin Modulators therapeutic use
Angioplasty adverse effects
Coronary Disease drug therapy
Coronary Vessels pathology
Drug-Eluting Stents adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1774-024X
- Volume :
- 5
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 19755329
- Full Text :
- https://doi.org/10.4244/eijv5i4a68