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A new cytotoxic iridoid from Callicarpa nudiflora.

Authors :
Mei WL
Han Z
Cui HB
Zhao YX
Deng YY
Dai HF
Source :
Natural product research [Nat Prod Res] 2010 Jun; Vol. 24 (10), pp. 899-904.
Publication Year :
2010

Abstract

A new iridoid, named nudifloside (1), together with three known compounds, was isolated from the EtOH extract of the aerial parts of Callicarpa nudiflora Hook. The structures were elucidated by a study of their physical and spectral data. Nudifloside (1) and the isolated known compound linearoside (2) displayed inhibitory effects towards chronic myelogenous leukaemia K562 cell line, with IC(50) values of 20.7 and 36.0 microg mL(-1), respectively.

Details

Language :
English
ISSN :
1478-6427
Volume :
24
Issue :
10
Database :
MEDLINE
Journal :
Natural product research
Publication Type :
Academic Journal
Accession number :
19753502
Full Text :
https://doi.org/10.1080/14786410802267544