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[Tissue-specific blocking of the EcoRI site adjacent to the pseudogene for mouse oncoprotein p53].
- Source :
-
Molekuliarnaia genetika, mikrobiologiia i virusologiia [Mol Gen Mikrobiol Virusol] 1990 Apr (4), pp. 17-8. - Publication Year :
- 1990
-
Abstract
- EcoRI fragments of DNA isolated from the different mouse organs were hybridized to radioactivity labelled probe specific for the gene of oncoprotein p53. The analysis of the blot-hybridization points to the existence of the specific blockage of an EcoRI site flanking a 3.3 kb fragment of DNA including the pseudogene p53, isolated from the skin tissue. The existence of a polymorphous EcoRI site localized distally to the pseudogene p53 has been demonstrated in the DNA of mice of different lines.
Details
- Language :
- Russian
- ISSN :
- 0208-0613
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Molekuliarnaia genetika, mikrobiologiia i virusologiia
- Publication Type :
- Academic Journal
- Accession number :
- 1973262