Back to Search
Start Over
Enantioselective synthesis of beta-trifluoromethyl-beta-lactones via NHC-catalyzed ketene-ketone cycloaddition reactions.
- Source :
-
Organic letters [Org Lett] 2009 Sep 17; Vol. 11 (18), pp. 4029-31. - Publication Year :
- 2009
-
Abstract
- The highly diastereo- and enantioselective synthesis of beta-trifluoromethyl-beta-lactones bearing two contiguous stereocenters was realized by chiral N-heterocyclic carbene-catalyzed formal cycloaddition reaction of alkyl(aryl)ketenes and trifluoromethyl ketones.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 11
- Issue :
- 18
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 19681591
- Full Text :
- https://doi.org/10.1021/ol901290z